Immunohistochemical staining showed increased degrees of cytoplasmic APC in cells taken care of with the ASO-miR129-5p-lentivirus although cells in GFP-lentivirus group or untransfected group confirmed only weak expression (Fig. 6A)

Also, miR-129-5p transfection did not decrease the luciferase action of the reporter construct transfected with mutant 39UTR of APC. Co-transfection of the miR-129-5p inhibitor, ASO-miR-129-5p, with miR-129-5p also eradicated the…