Damage checkpoint control.Table Similarities involving yeast and human SCD proteins (Continued)Tid Ubr Ycs (NDC) (UBR) (NCAPD) Part of the kinetochoreassociated Ndc complicated involved in chromosome segregation. E ubiquitin ligase (Nrecognin) that ubiquitite substrates inside the Nend rule pathway. Subunit in the condensin complicated.Collection of yeast SCD genes whose human ortholog contains an SCD and is recognized to become phosphorylated in STQ web sites Akl Bni (AAK) (FMN) Protein kise involved in endocytosis and actin cytoskeleton organization. Formin, nucleates the formation of linear actin filaments; involved in and mitotic spindle orientation. Component with the septin ring of the motherbud neck that is essential for cytokinesis. Needed for sister chromatid cohesion; a part of the D damage replication checkpoint. exonuclease and flapendonuclease involved in recombition, DSB and mismatch repair. Catalytic subunit of D polymerase (II) epsilon. Subunit of MRX complex involved in processing doublestrand D breaks, and telomere maintence. Regulatory subunit of protein phosphatase A (PPA). E ubiquitin ligase of your hectdomain class; features a function in mR export in the nucleus.Pol(MYBBPA) D Polymerase phi; not C.I. 11124 cost expected for chromosomal D replication; expected for the synthesis of rR. Subunit from the nuclear pore complicated (NPC); interacts with mR export factor Mexp and with Kapp. Involved in the recombitiol repair of doublestrand breaks. Important transcriptiol repressor of Ddamageregulated genes. Subunit of the condensin complex. Subunit of TFIID and SAGA complexes. Translation initiation issue eIFG, subunit from the mR capbinding protein complicated (eIFF).Nup (POM) Rad Rfx Smc Taf (RADL) (RFX) (SMC) (TAFB)Cdc Ctf Exo(SEP) (CHTF) (EXO)Pol Rad(POLE) (RAD)Tif (EIFG)Selection of yeast SCD genes whose human ortholog consists of phosphorylated STQ web sites Bub Cdc Cdc Hrr (BUB) (CDC) (FBXW) (CSNKD) Protein PubMed ID:http://jpet.aspetjournals.org/content/1/2/275 kise that play crucial roles in the Spindle Assembly Checkpoint. Cellcycle regulated activator of APCC, which can be required for metaphaseaphase transition. Fbox protein that controls cell cycle function, sulfur metabolism, and methionine biosynthesis. Protein kise involved in regulating vesicular trafficking, D repair, and chromosome segregation. Coiledcoil protein involved in the spindleassembly checkpoint. Transcription Tyr-D-Ala-Gly-Phe-Leu web aspect involved in celltypespecific transcription and pheromone response. Protein involved in D replication; component with the Mcm hexameric prereplicative complicated. Protein tyrosine phosphatase involved in cell cycle handle; regulates the phosphorylation state of Cdcp. Protein expected for mismatch repair in mitosis and meiosis as well as crossing over in the course of meiosis. Mismatch repair protein. Protein essential for establishment and maintence of sister chromatid condensation and cohesion. Kise involved in transcriptiol activation of osmostressresponsive genes; regulate progression.Rts Tom(PPPRA) (HUWE) Phosphorylated in STQ websites in mass spectrometry searches. Phosphorylated in STQ internet sites inside an SCD in mass spectrometry searches.Mad Mcm Mcm(MAD) (SRF) (MCM)Mih(CDCA)Mlh(MLH)Msh Pds(MSH) (APRIN)Sch(RPSKA)(regulation of Ace activity and cellular morphogenesis) pathway, whose function is crucial for daughter cellspecific transcription expected for cell separation. As a result, SCD proteins are enriched for roles revolving about the end of mitosis, in the mitotic networks that manage entry into aphase and telophase to the regulation and formation with the contractile ring duri.Damage checkpoint handle.Table Similarities involving yeast and human SCD proteins (Continued)Tid Ubr Ycs (NDC) (UBR) (NCAPD) Part of the kinetochoreassociated Ndc complex involved in chromosome segregation. E ubiquitin ligase (Nrecognin) that ubiquitite substrates in the Nend rule pathway. Subunit of the condensin complicated.Collection of yeast SCD genes whose human ortholog consists of an SCD and is known to become phosphorylated in STQ sites Akl Bni (AAK) (FMN) Protein kise involved in endocytosis and actin cytoskeleton organization. Formin, nucleates the formation of linear actin filaments; involved in and mitotic spindle orientation. Element of the septin ring with the motherbud neck that may be required for cytokinesis. Needed for sister chromatid cohesion; a part of the D harm replication checkpoint. exonuclease and flapendonuclease involved in recombition, DSB and mismatch repair. Catalytic subunit of D polymerase (II) epsilon. Subunit of MRX complex involved in processing doublestrand D breaks, and telomere maintence. Regulatory subunit of protein phosphatase A (PPA). E ubiquitin ligase of your hectdomain class; has a part in mR export from the nucleus.Pol(MYBBPA) D Polymerase phi; not expected for chromosomal D replication; necessary for the synthesis of rR. Subunit in the nuclear pore complex (NPC); interacts with mR export issue Mexp and with Kapp. Involved in the recombitiol repair of doublestrand breaks. Major transcriptiol repressor of Ddamageregulated genes. Subunit of your condensin complex. Subunit of TFIID and SAGA complexes. Translation initiation aspect eIFG, subunit of the mR capbinding protein complex (eIFF).Nup (POM) Rad Rfx Smc Taf (RADL) (RFX) (SMC) (TAFB)Cdc Ctf Exo(SEP) (CHTF) (EXO)Pol Rad(POLE) (RAD)Tif (EIFG)Collection of yeast SCD genes whose human ortholog includes phosphorylated STQ web sites Bub Cdc Cdc Hrr (BUB) (CDC) (FBXW) (CSNKD) Protein PubMed ID:http://jpet.aspetjournals.org/content/1/2/275 kise that play vital roles inside the Spindle Assembly Checkpoint. Cellcycle regulated activator of APCC, which is essential for metaphaseaphase transition. Fbox protein that controls cell cycle function, sulfur metabolism, and methionine biosynthesis. Protein kise involved in regulating vesicular trafficking, D repair, and chromosome segregation. Coiledcoil protein involved in the spindleassembly checkpoint. Transcription element involved in celltypespecific transcription and pheromone response. Protein involved in D replication; component from the Mcm hexameric prereplicative complex. Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdcp. Protein expected for mismatch repair in mitosis and meiosis also as crossing over for the duration of meiosis. Mismatch repair protein. Protein needed for establishment and maintence of sister chromatid condensation and cohesion. Kise involved in transcriptiol activation of osmostressresponsive genes; regulate progression.Rts Tom(PPPRA) (HUWE) Phosphorylated in STQ internet sites in mass spectrometry searches. Phosphorylated in STQ internet sites inside an SCD in mass spectrometry searches.Mad Mcm Mcm(MAD) (SRF) (MCM)Mih(CDCA)Mlh(MLH)Msh Pds(MSH) (APRIN)Sch(RPSKA)(regulation of Ace activity and cellular morphogenesis) pathway, whose function is crucial for daughter cellspecific transcription required for cell separation. Thus, SCD proteins are enriched for roles revolving about the finish of mitosis, in the mitotic networks that control entry into aphase and telophase for the regulation and formation in the contractile ring duri.