Product Name :
Rabbit anti Human ADAM DEC1
Description :
| Isotype IgG | Product Type Antigen Immunoaffinity Purified Polyclonal | Units 100 µg | Host Rabbit | Species Reactivity Human | Application ELISA Immunohistochemistry Western Blotting
Background :
Immunogen: Synthetic peptide derived from the human ADAMDEC1 protein.
Source :
ADAMDEC1 is expressed in the immune system, by dendritic cells and macrophages. It may play an important role in the control of the immune response and during pregnancy.1 Due to the partial lack of a disintegrin domain and the total lack of a cysteine-rich domain, this protein has been placed in a novel subclass of the ADAM gene family2. Synonyms: A disintegrin and metalloproteinase domain-like protein decysin 1,ADAM-like protein decysin 1 <
Product :
Product Form: Affinity Purified Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Antigen Immunoaffiinity Purification Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for Western blotting (1:400 dilution) and immunohistochemistry on paraffin embedded tissues (2-10 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. UniProtKB/Swiss-Prot Acession # O15204 2. Bates, E.E. et. atl., The ADAMDEC1 (decysin) gene structure: evolution by duplication in a metalloprtease gene cluster on chromosome 8p12. Immunogenetics. 2002 May;54(2):96-105. Epub 2002 Mar 16,
Related websites: https://www.medchemexpress.com/antibodies.html
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