Product Name :
Sphingomyelin Synthase 1 (SMS1)
Description :
| Product Type Blocking Peptide | Units 50 µg | Species Reactivity Human | Application Western Blotting
Background :
Immunogen: Synthetic peptide derived from human SMS1 protein
Source :
Sphingomyelin Synthase is a bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) in addition to performing the inverse reaction. The direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. It directly and specifically recognizes the choline head group on the substrate. It also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. It may not function strictly as a SM synthase and is inhibited by bacterial PC-phospholipase C inhibitor D609. It is localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. It can be possibly present on the brain, heart, kidney, liver, muscle and stomach. Synonyms: SMS1, Sphingomyelin synthase 1,Transmembrane protein 23, Medulla oblongata-derived protein, Protein Mob <
Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline Concentration: See vial for concentration
Specificity :
Applications :
For use with SMS1 polyclonal antibodies (Cat. No. X2065P and X1701P). Functional Analysis: Western Blotting
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Huitema K, van den Dikkenberg J, Brouwers JF, Holthuis JC Identification of a family of animal sphingomyelin synthases. EMBO J. 2004 Jan 14;23(1):33-44. Epub 2003 Dec 18.
Related websites: https://www.medchemexpress.com/antibodies.html
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