Human Kallikrein 3/PSA Protein 2520

Additional Information:
accession P07288|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundKallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), is the most useful biomarker for prostate cancer (PCa). KLK3 is suggested to play a role in regulating cancer growth through anti-angiogenic activity in vivo and in vitro.|molecular weightThe protein has a predicted MW of 27.93 kDa. Due to glycosylation, the protein migrates to 32-38 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Human Kallikrein 3/PSAProtein 2520proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceKallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), is the most useful biomarker for prostate cancer (PCa). KLK3 is suggested to play a role in regulating cancer growth through anti-angiogenic activity in vivo and in vitro.Protein namesProstate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase)Gene namesKLK3,KLK3 APSProtein familyPeptidase S1 family, Kallikrein subfamilyMass28741DaFunctionHydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.Catalytic activityCATALYTIC ACTIVITY: Reaction=Preferential cleavage: -Tyr-|-Xaa-.; EC=3.4.21.77;Subellular locationSecreted.StructureForms a heterodimer with SERPINA5.Target Relevance information above includes information from UniProt accession: P07288The UniProt Consortium|