Name :
FITC-Labeled Human CD38 Protein, His Tag
Background :
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Biological Activity :
Immobilized Anti-CD38 Antibody (Daratumumab), Human IgG1 at 2 μg/mL (100 μL/well) can bind FITC-Labeled Human CD38, His Tag (Cat. No. CD8-HF2H5) with a linear range of 1.25-10 μg/mL (QC tested).
Species :
Source :
FITC-Labeled Human CD38, His Tag (Cat. No. CD8-HF2H5) is expressed from human HEK293 cells. It contains AA Val 43 – Ile 300 (Accession # NP_001766). It is the FITC labeled form of Human CD38 Protein, His Tag (Cat. No. CD8-H5224).
Tag :
Synonyms :
（Synonym）CD38,T10,cADPr hydrolase 1
Purity :
（Purity）>90% as determined by SDS-PAGE.
Storage and Stability :
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin Level :
（Endotoxin）Less than 1.0 EU per μg by the LAL method.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Protein Structure :
Refactoring Approach :
Please see Certificate of Analysis for specific instructions.
Protein Labeling :
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