Product Name :
Lonapalene
Synonym :
Chemical Name :
CAS NO.:
91431-42-4
Molecular formula :
C16H15ClO6
Molecular Weight:
338.74 g/mol
Classification :
MedChemExpress Products > Life Sciences > Lonapalene
Description:
Lonapalene is a prodrug that can be converted to its active form, lonaprazan. It is used in the treatment of asthma and inflammatory bowel disease. Lonapalene inhibits the enzyme phospholipase A2 (PLA2) by binding to the hydroxyl group of arachidonic acid, which prevents arachidonic acid from being released as a substrate for PLA2. This inhibition results in an anti-inflammatory effect. Lonapalene also inhibits other enzymes such as cyclooxygenase and lipoxygenase, which are involved in the synthesis of prostaglandins and leukotrienes. Lonapalene has been shown to have anti-inflammatory activity due to its ability to inhibit prostaglandin synthesis, which may be due to its ability to bind with fatty acids.br>br>
Purity :
>98%
Specifications :
10 mM * 1 mL
Price.:
715
Price unit :
$
Inventory :
In stock
Related websites: https://www.medchemexpress.com
162635-04-3 SMILES 51364-51-3 Synonym PMID:30521272 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com