**Background**
The c-myc protein is a well-known transcription factor that plays a pivotal role in the regulation of growth-related gene transcription, cell cycle progression, and apoptosis. Due to its ability to drive uncontrolled cellular proliferation, c-myc is frequently overexpressed in various malignancies and is considered a primary driver of oncogenesis. In particular, the role of c-myc in the growth of human breast cancer has been extensively documented, making it a critical target for therapeutic intervention and molecular study. Understanding the interactions of the c-myc protein is essential for developing strategies to inhibit tumor growth. In this context, we will introduce a synthetic tool for studying this protein – c-Myc Peptide.
**Definition**
c-Myc Peptide is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of the human c-myc protein, with the sequence Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu (EQKLISEEDL).
**In Vitro Studies**
According to the c-Myc Peptide description, this peptide serves as a representative fragment of the human c-myc protein involved in transcriptional regulation. Regarding c-Myc Peptide in vitro activity, research indicates that c-myc plays a critical role in the growth of breast cancer cells. Specifically, studies utilizing phosphorothioate antisense oligonucleotides to inhibit c-myc expression have identified its essential role in the proliferation of human breast cancer cell lines. The c-Myc Peptide formula (C53H87F3N12O23) and its molecular weight of 1317.32 ensure high specificity for research applications involving the C-terminal region of the protein. This peptide is particularly useful for researchers investigating c-Myc Peptide Cancer mechanisms and the regulation of growth-related genes. In conclusion, c-Myc Peptide is a synthetic C-terminal fragment of human c-myc used to study the regulation of gene transcription and cancer cell growth.
Keywords
c-Myc Peptide, 2918768-02-0, c-Myc, Myc, Inhibitor, inhibitor, inhibit
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