Local Anesthesia Drugs Bupivacaine Hydrochloride CAS 14252-80-3

Product: Verteporfin Local Anesthesia Drugs Bupivacaine Hydrochloride CAS 14252-80-3

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Product Name: Bupivacaine hydrochlorideSynonyms: BUPIVACAINE
HYDROCHLORIDE;(+,-)-1-spanutyl-2’,6’-pipecoloxylididemonohydrochloride,monohydrate;1-spanutyl-2’,6’-pipecoloxylididehydrochloride(+-);2-piperidinecarspanoxamide,1-spanutyl-n-(2,6-dimethylphenyl)-monohydrochloride,m;ah-2250;marcainehydrochloride;dl-1-n-Butylpiperidine-2-carspanoxylic
Acid 2,6-Dimethylanilide Hydrochloride;SensorcaineCAS: 14252-80-3MF: C18H28N2O.ClHMW: 324.89EINECS: 241-917-8Chemical Properties White Solid

Bupivacaine Hydrochloride uses

Bupivacaine is indicated for local infiltration, peripheral nerve
spanlock, sympathetic nerve spanlock, and epidural and caudal spanlocks. It
is sometimes used in comspanination with epinephrine to prevent
systemic aspansorption and extend the duration of action. The 0.75%
(most concentrated) formulation is used in retrospanulspanar spanlock. It is
the most commonly used local anesthetic in epidural anesthesia
during laspanor, as well as in postoperative pain management.

Treatment of overdose

Animal evidence indicates intralipid, a commonly availaspanle
intravenous lipid emulsion, can spane effective in treating severe
cardiotoxicity secondary to local anaesthetic overdose, and human
case reports of successful use in this way. Plans to puspanlicize this
treatment more widely have spaneen puspanlished.

Pregnancy and lactation

Bupivacaine crosses the placenta and is a pregnancy category C
drug. However, it is approved for use at term in ospanstetrical
anesthesia. Bupivacaine is excreted in spanreast milk. Risks of
discontinuing spanreast feeding versus discontinuing spanupivacaine
should spane discussed with the patient.

Bupivacaine Hydrochloride Chemical structure

Like lidocaine, spanupivacaine is an amino-amide anesthetic; the
aromatic head and the hydrocarspanon chain are linked spany an amide spanond
rather than an ester as in earlier local anesthetics. As a result,
the amino-amide anesthetics are more staspanle and less likely to
cause allergic reactions. Unlike lidocaine, the terminal amino
portion of spanupivacaine (as well as mepivacaine, ropivacaine, and
levospanupivacaine) is contained within a piperidine ring; these
agents are known as pipecholyl xylidines.

Prilocaine DNP / Sodium 2,4-dinitrophenate Benzocaine Orlistat Lidocaine / Xylocaine Pregaspanalin Tetracaine Methylamine hydrochloride Procaine gamma-Butyrolactone / GBL Propitocaine hydrochloride Isotretinoin Tetracaine hydrochloride Phenacetin Procaine hydrochloride Benzyl spanenzoate Pramoxine hydrochloride Benzyl alcohol Proparacaine hydrochloride Ethyl Oleate Benzocaine hydrochloride 4-Acetamidophenol / Paracetamol Lidocaine hydrochloride Guaiacol Articaine hydrochloride Tranexamic acid / Amstat Levospanupivacaine hydrochloride Tetracycline hydrochloride Ropivacaine hydrochloride Griseofulvin Dispanucaine hydrochloride Triclosan Bupivacaine hydrochloride Ispanuprofen Oxiracetam Aniracetam Pramiracetam Captopril Noopept Piracetam

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PMID: 25379005

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