ted. Extra file 10. Enriched terms in up-regulated genes involving Supplemented Infected vs Control Infected. Extra file 11. Enriched terms inside the list of differentially upregulated genes in between the groups Handle Infected vs Supplemented Infected. Extra file 12. Typical liveweight and age (standard deviation) for each and every group in the starting and end with the experiment. Extra file 13. Composition of your control protein and supplemented protein diets. Extra file 14. Bromatological composition (g kg-1 of dry matter at 100 ) and energy (MJ) with the diets’ components. Additional file 15. Bromatological RSK4 manufacturer Analysis in the eating plan. Added file 16. List of ovarian RNA samples, their concentration, 260/280 and 260/230 absorbance ratios. Extra file 17. EM estimation algorithm procedure. More file 18. Statistical methodology used within the Enrichment evaluation. Extra file 19. Protein Network evaluation. Acknowledgements Not applicable. Arrive suggestions statement This study was carried out in compliance together with the ARRIVE suggestions. Authors’ contributions P.S.H. carried out the in vivo and laboratory experiments, analysed the information and wrote the manuscript. C.M.S.C. carried out the in vivo and laboratory experiments. R.C.L. performed the statistical analyses, assisted with manuscript writing and revision. D.G.C. helped with qPCR arranging and qPCR data evaluation. L.M.K. cultivated and offered the Haemonchus contortus larvae. S.M.T. assisted in the arranging of experiments. H. L. elaborated the study design and style and arranging, assisted in the manuscript revision. The author(s) study and approved the final manuscript. Author’s details Paula Suarez-Henriques is a veterinary surgeon using a Master in Animal Science along with a Doctorate in Animal Science. She obtained both degrees inside the last six years at the University of S Paulo in Brazil. In July 2020, she presented a part of her doctorate investigation in the Society for the Study of Reproduction virtual meeting. Just before that, she worked as a veterinarian clinician along with a study assistant in laboratories studying molecular pathology of breast cancers, cell and molecular biology in mammary gland improvement, and numerous myeloma resistance to alkylating agents. Funding We thank the National Council for Scientific and Technological Analysis -(CNPq – Brazil) and CAPES for the financial assistance with Paula SuarezHenriques’ PhD studentship bursary quantity 141846/2017 and, for funding the costs of reagents and gear vital for the accomplishment of this investigation project, with process numbers CNPq 311008/2016-0 and CNPq RIPK2 Species 420373/2016. We also thank S Paulo Research Assistance FoundationSupplementary InformationThe on-line version consists of supplementary material offered at doi. org/10.1186/s12917-021-03020-7. Further file 1: Table S1. RNA sequencing information quality summary. Additional file 2: Table S2. Number of sequences and Sequencing depth generated by RNA sequencing.Suarez-Henriques et al. BMC Veterinary Analysis(2021) 17:Page 22 of(FAPESP) approach numbers 2017/50451 and 2017/18086-0, for extra funding for reagents. Availability of information and materials The datasets employed and/or analysed for the duration of the existing study are readily available in the Extra files. The files which are not in this section might be offered beneath affordable request to Dr. Helder Louvandini e-mail address: [email protected] approval This analysis project, with its protocol and procedures employed, were eth