Product Name :
Mouse anti Human bcl-xl

Description :
| Clone 2H12 | Isotype IgG2a | Product Type Monoclonal Antibody | Units 100 µg | Host Mouse | Species Reactivity Human Mouse Rat | Application Western Blotting

Background :
Mice were immunized with a synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence. Immunogen: A synthetic peptide corresponding to amino acids 3 to 14 of the human bcl-xl sequence

Source :
Overexpression of bcl-xl to other bcl-2 members is believed to promote cell survival. The ratio of bcl-xl to other family members is believed to modulate the apoptotic process. Synonyms: bcl-xl, mouse anti human bcl xl, bclxl <

Product :
Provided as solution in phosphate buffered saline. Product Form: Unconjugated Purification Method: Protein A/G Chromatography Concentration: See vial for concentration

Specificity :

Applications :
Application: Western Blot at 1-5 ug/ml. Functional Analysis: Western Blotting Positive Control: Human, mouse and rat thymocytes

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1) L.H. Boise, et. al. (1993) Cell, 74:597-608. 2) Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834 3) Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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