Product Name :
Mouse anti Human Cyclin Dependant Kinase 4

Description :
| Clone DCS31.2 | Isotype IgG1 | Product Type Monoclonal Antibody | Units 100 µg | Host Mouse | Species Reactivity Human Mouse Rat | Application Immunocytochemistry Immunofluorescense Immunoprecipitation Western Blotting

Background :
The immunogen used for the immunization of the mice was a recombinant cdk 4 (34 kDa) protein.

Source :
Cdk4 is a critical regulator in cell cycle progression between G1 and S. Synonyms: hcdk4; cyclin dependant kinase 4; Cell division protein kinase 4; PSK-J3 <

Product :
Provided as solution in phosphate buffered saline with 0.08% sodium azide. Product Form: Unconjugated Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration

Specificity :
The antibody has no cross reaction with other cdk’s and does not co-precipitate the D-type cyclins bound to cdk4.

Applications :
Applications: Western Blot, Immunohistochemistry, Immunoprecipitation (unbound cdk4 only). Functional Analysis: Western Blotting

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1) S. Eledge, (1997) Science, 274 , 1664-1672.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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