Product Name :
Mouse anti Human Fetoprotein

Description :
| Clone C3 | Isotype IgG2a | Product Type Monoclonal Antibody | Units 100 µg | Host Mouse | Species Reactivity Dog Human Pig | Application Immunohistochemistry

Background :
Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with purified human alpha-fetoprotein and mouse myeloma cells.

Source :
Alpha-Feto Protein (AFP) is a protein produced by the fetus, which is excreted into the amniotic fluid and into the mother’s bloodstream through the placenta. The amount of AFP, both in the maternalÕs blood and in the amniotic fluid, at particular periods during the pregnancy, may be associated with the presence of neural tube defects or chromosomal problems in the baby. AFP synthesis occurs in tissues including the gut, liver and fetal yolk sac. AFP expression may be seen in germ cell neoplasma and in liver carcinoma. Synonyms: AFP <

Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Protein A/G Chromatography Concentration: See vial for concentration

Specificity :

Applications :
Antibody can be used for immunohistochemistry on formalin-fixed, paraffin embedded tissues (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Immunohistochemistry Positive Control: HepG2 cells

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1. Yazova AK; et al. ‘Human alpha-fetoprotein epitopes as revealed by monoclonal antibodies.’ Immunology Letters, 1990 Sep, 25(4):325-30. 2. Sato, Y., et al. ‘Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.’ Blood, 106, 756-763 (2005).

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites:
Popular product recommendations:
CD8 alpha Antibody
Anti-Mouse IFN gamma Antibody (H22)
Hsp90 beta Antibody: Hsp90 beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Hsp90 beta. It can be used for WB,ICC/IF,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse, Rat.