Product Name :
Mouse anti Human p13

Description :
| Clone BM-3 | Isotype IgG1 | Product Type Monoclonal Antibody | Units 100 µg | Host Mouse | Species Reactivity Human | Application Flow Cytometry Immunohistochemistry (frozen)

Background :
Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with nuclei from Pokeweed mitogen stimulated with peripheral blood lymphocytes and mouse myeloma cells.

Source :
Used as a marker for human myeloid cells. p13 protein is a nuclear antigen expressed in human granulocytes and monocytes in lymphoid and non-lymphoid tissues and is expressed during the early phases of myeloid differentiation. <

Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration

Specificity :

Applications :
Antibody can be used for immunohistochemistry on frozen tissues sections and flow cytometry. Not for use on paraffin embedded tissue sections. Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: HL-60 cells

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1. Epstein, A.L. and Clevenger, C.V. ‘Identification of nuclear antigens in human cells by immunofluorescence, immunoelectron microscopy, and immunobiochemical methods using monoclonal antibodies.’ Progress in Nonhistone Protein Research, Vol. 1, Isaac Bekhor, ed., 1985, CRC Press, Boca Raton, FL, pp. 117-137 2. Murao, S., et al. ‘Expression of maturation-specific nuclear antigens in differentiating human myeloid leukemia cells.’ Cancer Research 1985: 45:791-795

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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