Product Name :

Description :
| Units 200 µg | Host Rabbit | Application ELISA Immunofluoresence Immunohistochemistry (paraffin) Western Blotting

Background :
Immunogen: Cell preparation of Borrelia burgdorferi

Source :
The antibody is well suited to detect Borrelia in tissue slices and tissue extracts. Borrelia burgdorferi is a species of bacteria belonging to the class of spirochetes. Borrelia burgdorferi is the agent of Lyme Disease, a vector-borne disease transmitted by ticks (Ixodes ricinus and Ixodes dammini). Borrelia is widely distributed in North America and Europe. Borrelia burgdorferi, cross-reactivity with Borrelia hermsii and Borrelia parkerii as well as Treponema pallidum. In Western blotting bands are seen at 83kDa, 41kDa, 34kDa, 31kDa. Additional lower MW bands may also be observed. . <

Product :
Purified IgG in PBS pH7.2, contains sodium azide (0,09%)** Purification Method: Purified IgG in PBS pH7.2, contains sodium azide (0,09%)** Secondary Reagents: Anti-Rabbit IgG:Biotin-conjugate (Art. No. ZU101) in combination with Streptavidin:HRPO (Art. No. ZU054) or Streptavidin:AP (Art. No. ZU051) Concentration: 1 mg/ml

Specificity :
Species Reactivity: Borrelia, (Treponema)

Applications :
IHC(P), WB, IFA, ELISA Incubation Time: 60 min at RT or 18 hr at 2-8°C Working Concentration: (liquid conc.) WB: 1 µg/ml, IHC: 5 µg/ml

Storage :

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1. Buechner S A , Winkelmann R K, Lautenschlager S ,Gilli L , Rufli T (1993) Localized scleroderma associated with Borrelia burgdorferi infection. Clinical, histologic, and immunohistochemical observations Journal of the American Academy of Dermatology. 29(2 Pt 1):190-6. 2. Quatresooz P., Piérard G. E. (2009) Skin Homing of Treponema pallidum in Early Syphilis: An Immunohistochemical Study Applied Immunohistochemistry & Molecular Morphology: Volume 17 – Issue 1 – pp 47-50 3. Arrese Estrada J; Mélotte P; Hermanns J F; Piérard G E (1991) Immunohistochemistry of Borrelia type spirochetes Annales de dermatologie et de vénéréologie 118(4):277-9.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites:
Popular product recommendations:
Glutaminase Antibody: Glutaminase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 73 kDa, targeting to Glutaminase. It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.