Product Name :
PDX1
Description :
| Product Type Blocking Peptide | Units 50 µg | Application Blocking Peptide
Background :
Source :
This peptide is the immunogen used to make Cat # X2755P.PDX1 ctivates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5′-[CT]TAAT[TG]-3′. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell. Blocking Peptide to Cat # X2755P. Synonyms: Pancreas/Duodenum Homeobox Protein 1; Glucose-sensitive factor; Insulin promoter factor 1; Insulin upstream factor 1; <
Product :
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Concentration: See vial for concentration
Specificity :
Applications :
Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Neutralizing
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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