Product Name :
Rabbit anti Alkylphenols (nonylphenol; octylphenol)

Description :
| Clone Polyclonal | Isotype Ig | Product Type Primary Antibodies | Units 0.5 ml | Host Rabbit | Application ELISA Immuno-affinity-chromatography

Background :
Rabbit Ig purified by affinity purification on a caprylic acid coupled column Immunogen: BSA-C6-alkylphenol conjugate

Source :
Alkylphenols are used as starting material for the production of surface active substances, detergents, pesticides, paints, textile and paper. It is released during the production and use of these products. Alkylphenols are recognized as endocrine disruptors, in particular estrogenic endocrine disruptors. <

Product :
Each vial contains 0.5 ml 0.8 mg/ml of affinity purified polyclonal antibody in phosphate buffered saline (pH 7.2) containing 0.02% sodium azide.

Specificity :
Target: Alkylphenols (a family of comparable compounds; as an example nonylphenol is given), CAS no.: 104-40-5 The antibody was tested for specificity using 2 conjugates: BSA-C6-AP and BSA-C8-AP Species Reactivity: The antibody was tested for specificity using 2 conjugates: BSA-C6-AP and BSA-C8-AP Cross Reactivity with BSA-C6-AP or BSA-C8-AP: Octylfenol 100% 100% 4-tert-Butylphenol 6% 7% 2-sec-Butylphenol 1% 0% 4-pentylphenol 556% 367% 4-n-heptylphenol 256% 194% 4-n-propylphenol 33% 10% 2-n-propylfenol 0% 0% 4-Isopropylphenol 6% 10% 4-n-hexylphenol 300% 500% 4-chloro-2-cyclo-hexylphenol 0% 1% nonylphenol(tech) 12% 18% 4-n-nonylphenol 30% 50%Bisphenol A 8% 7% 4-cumylphenol n.d 200% 4-Octylphenol n.d 10% 4,4′-(ethylidene) bisphenol n.d 10% Bisphenol A diglycidyl ether.d 100% Phenol n.d 4,4’cyclohexylidene bisphenol n.d 200% Bis-(4-hydroxyphenyl)-methane n.d 200%

Applications :
The antibody may be used in ELISA and IAC.For ELISA, the recommended dilution is 1:300 to 1:3000, depending on the conjugate used for detection. For positive controls ELISA plates are coated with 400 ng/ml BSA-conjugated C6/C8-alkylphenol.

Storage :
This working antibody solution is stable for at least 7 days at 4 ┬░C.Precautions should be taken upon storage for longer periods. Problems of long term stability may occur with highly diluted solution. For long storage purposes in solution the addition of sodium azide at 0.02 % is advised with the appropriate precautions of use. Shipping Conditions: At ambient temperature

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1. Meulenberg EP, Koopal K, Rhemrev R. (2005) Immunoassays for alkylphenolic pollutants with endocrine disrupting activity. Intern. J. Environ. Anal. Chem. 85, 871-883.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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