Product Name :
Rabbit anti Human KLF14
Description :
| Isotype IgG | Product Type Antigen Immunoaffinity Purified Polyclonal | Units 100 µg | Host Rabbit | Species Reactivity Human | Application Immunohistochemistry Western Blotting
Background :
Immunogen: Synthetic peptide derived from the human KLF14 protein
Source :
KLF14 is a member of the KrŸppel-like factor family of transcription factors. It regulates the transcription of various genes, including TGF RII (the type II receptor for TGF ). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression. Synonyms: Krueppel-like factor 14, BTE-binding protein 5 <
Product :
Product Form: Affinity Purified Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Antigen Immunoaffiinity Purification Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for immunohistochemistry (2-4 µg/ml) and Western blotting (1-2 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Human tonsil
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Truty, M.J., et al. ‘Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling.’ J. Biol. Chem., 284, 6291-6300 (2009)2. Swamynathan, S.K. ‘Krüppel-like factors: three fingers in control.’ Hum. Genomics, 4, 263-270 (2010)3. Parker-Katiraee, L., et al. ‘Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.’ PLoS Genet., 3, e65, (2007)
Related websites: https://www.medchemexpress.com/antibodies.html
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