Product Name :
Rabbit anti Human Stanniocalcin-1 (STC1)
Description :
| Isotype IgG | Product Type Antigen Immunoaffinity Purified Polyclonal | Units 100 µg | Host Rabbit | Species Reactivity Human | Application ELISA Western Blotting
Background :
Immunogen: Synthetic peptide derived from the human STC-1 protein.
Source :
Stanniocalcin 1 is a secreted disulfide-linked homodimeric glycoprotein belonging to the stanniocalcin family of proteins. It is widely expressed and has endocrine/paracrine/autocrine functions relating to calcium and phosphate homeostasis, reproduction, and development. In the ovary, it has been shown to be a paracrine hormone that regulates granulosa cell function. It also has been known to. stimulate renal phosphate reabsorption, and could therefore prevent hypercalcemia. Synonyms: STC1 <
Product :
Product Form: Affinity Purified Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Antigen Immunoaffiinity Purification Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for immunohistochemistry (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: Expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid. In the kidney, expression is confined to the nephron, specifically in the distal convoluted tubule and in the collecting tubule. Not detected in the brain, liver, spleen, peripheral blood leukocytes,adrenal medulla.
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. Jeffrey K.J., Reddel R.R., ‘Characterization of the human stanniocalcin 1 gene.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases 2. Olsen H.S., Cepeda M.A., Zhang Q.-Q., Rosen C.A., Vozzolo B.L., Wagner G.F., Human stanniocalcin: a possible hormonal regulator of mineral metabolism.Proc. Natl. Acad. Sci. U.S.A. 93:1792-1796(1996) [PubMed: 8700837] [Abstract]
Related websites: https://www.medchemexpress.com/antibodies.html
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