Product Name :
Rabbit anti Human SURF1
Description :
| Isotype IgG | Product Type Polyclonal Antibody | Units 100 µg | Host Rabbit | Species Reactivity Human | Application Western Blotting
Background :
Immunogen: Full length recombinant human Ssu72 protein
Source :
Human Ssu72 is a highly conserved homologue of yeast Ssu72, a CTD phosphatase and a component of the polyadenylation/termination machinery. The human Ssu72 is located on Chromosome 1p36 and seems to represent a single gene. It was identified as a pRb binding factor and was also shown to interact with TFIIB and yeast PTA1. Rabbit polyclonal antibodies were raised against SSU72 fusion protein. The ABs recognize a single band of ~30 Kda on immunoblots of various human cell lines but do not work well on mouse tissues. Synonyms: Human Ssu72 <
Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration
Specificity :
Applications :
Antibody can be used for Western blot (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions. Functional Analysis: Western Blotting Positive Control: MCF-7 and Cos-7 cells
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1. St-Pierre, B., et al. ‘Conserved and specific functions of mammalian ssu72’ Nucleic Acids Res. 2005, 33, 464-477 2. Krishnamurthy, S., et al. ‘Ssu72 is an RNA polymerase II CTD phosphatase’ Mol. Cell 2004, 14, 387-394 3. Steinmetz, EJ., Brow, DA. ‘Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcription’ Mol Cell Biol 2003, 23, 6339-6349
Related websites: https://www.medchemexpress.com/antibodies.html
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