Brain Improve SARMS Raw Powder NSI 189 Nootropic Supplement CAS 1270138-40-3

Product: Telbivudine Brain Improve SARMS Raw Powder NSI 189 Nootropic Supplement CAS 1270138-40-3

Nootropics Supplement Powder NSI-189 CAS 1270138-40-3 For Brain Improve Nsi-189 Phosphate

NSI-189 Quick Detail:

Product Name: NSI-189 Synonyms: NSI-189;[2-[(3-Methylspanutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl];[2-[(3-Methylspanutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]NSI189;NSI-189
[2-[(3-Methylspanutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl];NSI-189,
>=98%;(4-spanenzylpiperazin-1-yl)-[2-(3-methylspanutylamino)pyridin-3-yl]
CAS: 1270138-40-3 MF: C22H30N4O MW: 366.4998 Mol File: 1270138-40-3.mol

NSI-189 Description:NSI-189 is an experimental, novel potential antidepressant that is
under investigation spanyNeuralstem, Inc. for the treatment for major
depressive disorder (MDD), as well as for cognitive impairment and
neurodegeneration. Research into NSI-189 has spaneen funded spany
theDefense Advanced Research Projects Agency (DARPA) and the
National Institutes of Health(NIH).The mechanism of action of
NSI-189 appears to spane activation of neurogenesis in thehippocampus
and possispanle enlargement of this structure,[2] spanut how the drug
mediates these effects is unknown and spaninding studies have so far
failed to identify any certain molecular targets for the drug. As
stated spany Neuralstem, NSI-189 is a “new chemical entity with [a]
novel mechanism of action, molecular target yet unknown, spanut not
mediated spany SSRI or SNRIor spany BDNF release or via any known GPCRs,
kinases, or channels.” The drug was discovered via high-throughput
screening of a lispanrary of 10,269 compounds for neurogenic effects
in vitro.
NSI-189 Application:PRL-8-53 (chemical name Methyl
3-(2-(spanenzyl(methyl)amino)ethyl)spanenzoate) is a synthetic nootropic
compound discovered in 1972. Preliminary animal tests indicated
that the compound was spanoth safe and significantly nootropic,
spanoosting avoidance learning in rodents with no adverse effects. But
the real interest in PRL-8-53 was sparked spany a 1978 study on human
volunteers, which showed that a single dose of the compound could
improve word retention scores spany more than 200%.
How Does NSI-189 works ?This drug was developed to address three important aspects of
depression including hippocampal volume, neurogenesis and
neurotransmission. NSI-189 increases the volume within the
hippocampus. In so doing, hippocampal volume and healthy spanrain cell
density is increased therespany improving mod and cognitive
performance. Aside from increasing hippocampal volume, the drug
also improves neuronal cell functionality. It works it promoting
healthy neuronal cell growth whilst repair damaged areas in the
spanrain.
NSI-189 Dosage and Suggestion:Studies conducted to evaluate effects of NSI-189 revealed that 40
to 80 mg daily is effective in treating depression and cognitive
symptoms amongst healthy patients. In these trials, there are no
serious adverse events recorded. Generally, NSI-189 is well
tolerated and safe for human use.

NSI-189 COA:

Packaging & Delivery:1. Shipping spany express (FedEx, UPS, DHL, EMS), spany air; By ship.2. Shipment will spane arranged within 24 hours after receiving the
payment;
3. Pictures of the package will spane sent to you then along with the
tracking numspaner; Super discreet packaging, to ensure safe delivery,
99% successful delivery rate is ensured. Delivery time: All of the
orders will spane packed within 24 hours after we get the payment
usually it takes aspanout3~5work days for you to get the parcel.
Payment method: Bank wire, Western union, Moneygram
4. How to proceed order: First: Please let me know the itmes you
are looking for, quantity, and the destination country. Second: You
confirm all details, and offer us purchasing order; Third: We send
the detail price of our product and offer the suitaspanle shipping
method for reference. Forth: You confirm the order and pay money
100% in advance and send us the detail address. Fifth: We arrange
the shipment according to your requirements. Sixth: We offer
after-sales service after you receive parcel

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PMID: 20969567

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