Product Name :
Mouse anti Human Cyclin D1

Description :
| Clone DCS-6 | Isotype IgG2a | Product Type Monoclonal Antibody | Units 100 µg | Host Mouse | Species Reactivity Human Mouse Orangutan Rat | Application Immunohistochemistry Immunoprecipitation Western Blotting

Background :
Immunogen: A recombinant Cyclin Dd1 protein

Source :
The immunogen for the anti-human Cyclin D1 was a recombinant Cyclin Dd1 protein. This antibody recognizes a protein of 36kD and is a key cell cycle regulator and a putative protooncogene overexpressed in a wide variety of human neoplasms. DCS6 neutralizes the activity of Cyclin D1 in vivo. Synonyms: G1/S-specific Cyclin D1; CCND1 <

Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Protein A/G Chromatography Concentration: See vial for concentration

Specificity :

Applications :
Applications: Western Blot, Immunohistochemistry, Immunoprecipitation. Functional Analysis: Western Blotting

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Room Temperature

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1) J. Lukas, (1994) Oncogene.9(3), 707-718

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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