Product Name :
Mouse anti Human p15 – ink4b

Description :
| Clone DCS114.1 | Isotype IgG1 | Product Type Monoclonal Antibody | Units 100 µg | Host Mouse | Species Reactivity Human | Application Immunocytochemistry Immunohistochemistry (paraffin) Immunoprecipitation Western Blotting

Background :
Mice were immunized with a his-tagged recombinant full length p15 protein recognizing a 15kDa protein

Source :
The p15ink4b tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16ink4a and p19ink4d. p15ink4b is a specific inhibitor of cdk4/cdk6, and is periodically expressed during cell cycle. Synonyms: hp15; p15 ink4b; Cyclin-dependent kinase 4 inhibitor B; Multiple tumor suppressor 2 <

Product :
Provided as solution in phosphate buffered saline with 0.08% sodium azide Product Form: Unconjugated Purification Method: Ammonium Sulfate Precipitation Concentration: See vial for concentration

Specificity :

Applications :
1-5 ug /ml for Western Blot, Immunohistochemistry, and Immunoprecipitation (co-precipitates cdk4/cdk6) Functional Analysis: Western Blotting

Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature

Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References :
1) C. Sherr, (1995) Gene & Dev..9, 1149-1163 2) Sakellariou, S., et al. ‘Immunohistochemical Expression of P15 (INK4B) and SMAD4 in Advanced Gastric Cancer.’ Anticancer Research (2008), 28, 1079-1083

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites:
Popular product recommendations:
p53 Antibody (YA250)
FGFR1 Antibody
BNIP3 Antibody: BNIP3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 22 kDa, targeting to BNIP3. It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Mouse.