Product Name :
Mouse anti Human p16 – ink4a
Description :
| Clone DCS50.1 | Isotype IgG1 | Product Type Monoclonal Antibody | Units 100 µg | Host Mouse | Species Reactivity Human | Application Immunohistochemistry Immunoprecipitation Western Blotting
Background :
Immunogen: A recombinant full length p16 protein recognizing a 16kDa protein
Source :
The immunogen for the anti-human p16 was a recombinant full length p16 protein recognizing a 16kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c. p16ink4a is a specific inhibitor of cdk4/cdk6, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including melanoma and lung carcinoma. It can be used in immunohistochemistry as an indicator of HPV infection in cervical and head and neck (pre)malignancies. Synonyms: hp16; p16 ink4a; Cyclin dependent kinase inhibitor 2A, isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; CDK4I <
Product :
Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Protein A/G Chromatography Concentration: See vial for concentration
Specificity :
Applications :
Applications: Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6) Functional Analysis: Western Blotting
Storage :
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles Product Stability: See expiration date on vial Shipping Conditions: Ship at ambient temperature, freeze upon arrival
Caution :
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.
References :
1) J. Lukas et.al (1995) Nature., 375,503-506 2) L. Aagaard et.al. (1995), Intl. J. of Cancer 61(1) 115-120
Related websites: https://www.medchemexpress.com/antibodies.html
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